Information

Dermocone is the azole group medication. Fluconazole is used to treat vaginal yeast infections. It works by stopping the growth of common types of vaginal yeast.

---

Therapeutic Class

Anti-fungal

---

Dose and Direction of Use

• Swallow the tablet without breaking, chewing or crushing the tablet.
• Take the medicine orally once a week. Take the medicine at the same day of the week.
• Follow the dosing time and duration as per the prescription.

---

Mode of Action

Fluconazole acts by selectively inhibiting the fungal enzyme, lanosterol-14 demethylase whereby the lanosterol cannot be converted to ergosterol, the principle sterol of fungal membranes, is impaired. This leads to disruption of the membrane function and increase in membrane permeability which is responsible for its fungicidal action.

---

Uses

Tinea infections and Pityriasis versicolor

Onchomycosis

Vaginal candidiasis

Oropharyngeal candidiasis

Atrophic oral candidiasis  associated with dentures

---

Contraindications

Hypersensitivity to fluconazole

---

Precautions and Warning

Hepatic injury, anaphylaxis

Pregnancy Category: B

Nursing Mothers: Secreted in human milk, probably safe to use during breast feeding and can be used in infants with disseminated candida infection.

Pediatric Use: Not to be used below 4 weeks.

---