Information

FUNGIGO 150 is brand name of Fluconazole 150mg. This drug is active against fungi and used to treat fungal infections caused by Cryptococcal meningitis, dermatophytosis etc.

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Therapeutic Class

Antifungal- Azoles

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Dose and Direction of Use

Swallow the capsule whole by mouth. You can take it with or without food but it is better to take at a fixed time. Don't crush, chew or break the tablet. Follow the dose and duration as prescribed by the doctor.

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Mode of Action

In fungi, it inhibits the microsomal cytochrome P450 enzyme (14-alpha sterol demethylase) which is responsible for conversion of lanosterol to ergosterol. Azoles binf to 14-alpha sterol demethylase inhibiting the production of ergosterol . This inhibition disrupts membrane structure and function and thereby inhibits fungal cell growth.

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Uses

Fungal infections against C. albicans and Cryptococcus neoformans together with dermatophytes.

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Contraindications

Don't use this medicine if you have:

• Hypersensitivity to this medicine

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Precautions and Warning

• Consult with your doctor if you are pregnant or breast feeding woman before taking this medicine to understand the risk and benefit ratio.
• Talk to your doctor about past medical history like kidney problem, heart problem or liver problem before taking this medicine
• Don't double the dose for the missed one.
• Complete the prescribed dose and duration of medicine. Do not stop taking the medication suddenly without talking to your doctor.
• It may cause dizziness or drowsiness so avoid any activity that requires concentration unless you know how the medicine acts on you.
• Avoid drinking alcohol as it can worsen the side effects.

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