Information

GLUNIL-1 is brand name of Glimepiride 1mg. It belongs to oral hypoglycemic agent  that reduces high blood sugar.  It helps to prevent serious complications of diabetes like kidney damage and blindness.

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Therapeutic Class

Antidiabetics ( Sulphonylurea)

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Dose and Direction of Use

It is for oral administration. Don't crush, chew or break the tablet. Follow the dose and duration as prescribed by the doctor.

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Mode of Action

Glimepiride blocks the sulphonylurea receptor.This leads to closure of potassium channel and results in opening of calcium channel.There is rapid influx of calcium in the cells.This results in translocation of insulin containing granules into the plasma and insulin is released. 

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Uses

Type 2 Diabetes Mellitus

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Contraindications

Don't take this medicine if you have:

• Hypersensitivity to glimepiride
•  Type 1 Diabetes
• Diabetic coma
• Diabetic ketoacidosis
• Severe renal or hepatic function disorders.

 

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Precautions and Warning

• Consult with your doctor if you are pregnant or breast feeding woman before taking this medicine to understand the risk and benefit ratio.
• Talk to your doctor about past medical history like kidney problem or liver problem before taking this medicine
• Avoid any alcoholic drinks as it can worsen the risk of low blood sugar level.
• Take the medication as prescribed by the doctor with proper diret and exercise.
• Pack a biscuit or chocolate incase you suffer from low blood sugar level.
• Monitor your blood sugar level regularly while taking this medicine.
• Dose-related edema, weight gain, and anemia may occur. So, doctor should monitor such effects as well.

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