Information

Kmine is the drug that acts on nervous system for anesthesia. It contains ketamine 50mg/ml in 2ml ampoule that is used for induction and maintenance of anesthesia. It induces dissociative anesthesia, a trance-like state providing pain relief, sedation, and amnesia.

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Therapeutic Class

Anesthetics

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Dose and Direction of Use

• Follow the dose as per the prescription.
• Inject the medication by the trained person through appropriate route.

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Mode of Action

Ketamine binds non-competetively to the phencyclidine recognision site on N-methyl-D-aspartate(NMDA) receptors. It exerts effect at other sites including opioid receptor and muscarinic receptors and nicotinic acetylcholine receptors.

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Uses

• Induce loss of conscousness
• Relieve pain

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Contraindications

• High blood pressure
• Hypersensitivity

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Precautions and Warning

• Use the medication under the supervision of anesthesiologist only.
• Inject the medicaion by the trained person.
• Do not inject randomly by untrained person.
• Do not use the medication randomly without discussing with doctor.
• Use the medication with caution for the patient with blood pressure.

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