Ubilic-150
Tablet
Dose Type
Ursodeoxycholic Acid 150mg
Generic Name
National Healthcare Pvt. Ltd.
Manufactured By
Information
The active ingredient of Ubilic-150 is Ursodeoxycholic Acid, a bile acid which is normally present in bile. Ursodeoxycholic acid is an epimer of chenodeoxycholic acid. Its administration changes the composition of bile and may dissolve gallstones. It is used as a cholagogue and choleretic.
Therapeutic Class
Bile Acid Preparations/Anticholelithic Agent
Dose and Direction of Use
Take the medication as directed by your doctor and as mentioned on the label. Unless told differently, swallow the tablet with water.
Mode of Action
Ursodeoxycholic acid reduces elevated liver enzyme levels by facilitating bile flow through the liver and protecting liver cells. The main mechanism is anticholelithic. Although the exact process of Ursodeoxycholic acid's anticholelithic action is not completely understood, it is thought that the drug is concentrated in bile and decreases biliary cholesterol by suppressing hepatic synthesis and secretion of cholesterol and by inhibiting its intestinal absorption. The reduced cholesterol saturation permits the gradual solubilization of cholesterol from gallstones, resulting in their eventual dissolution.
Uses
- Treatment of primary biliary cirrhosis (PBC)
- Dissolution of gallstones
- Hepatobiliar disorder associated with cystic fibrosis in children aged 6 years to less than 18 years.
- Intrahepatic cholestatis of Pregnancy (ICP)
Contraindications
-
Don't use this medication if you have:
- Acute inflammation of the gallbladder or biliary tract.
- Occlusion of the biliary tract (occlusion of the common bile duct or a cystic duct).
- Frequent episodes of biliary colic.
- Radio-opaque calcified gallstones.
- Impaired contractility of the gallbladder.
- Non functioning gall bladder.
- Hypersensitivity to bile acids
- Inflammatory bowel disease
- Hepatic and intestinal conditions interfering with enterohepatic recirculation of bile acids
- Extrahepatic cholestasis
- Intrahepatic cholestasis
- Ileal resection
- Regional ileitis
- Ileal stoma
- Acute, chronic or severe liver disease
- Active duodenal ulcer
- Active gastric ulcer
- In paediatrci population with unsuccessful portoenterostomy or without recovery of good bile flow in children with biliary atresia
Precautions and Warning
- Ursodeoxycholic acid should be taken under medical supervision.
- Have regular liver function test.
- It contains lactose, so consult your doctor if you have tolerance to some sugar.
- Mention if you are taking any other medications like oral contraceptive drugs as it can affect the work of Ursodeoxycholic Acid.
- Consult with your doctor if you are pregnant or breast feeding woman before taking this medicine to understand the risk and benefit ratio.
- Talk to your doctor about past medical history like kidney problem or liver problem before taking this medicine
- Don't double the dose for the missed one.
- Complete the prescribed dose and duration of medicine.