SINEX SUSP
Suspension
Dose Type
Information
SINEX SUSP is brand name of Pseudoepehdrine + CPM + Paracetamol. This combination medicine is used to temporarily treat symptoms caused by common cold, flu, allergies and bronchitis.
Therapeutic Class
- Pseudoepehdrine (Decongestant)
- Chlorpheniramine (Antihistamine)
- Paracetamol (Non-steriodal Anti-Inflammatory Drug)
Dose and Direction of Use
Carefully measure the dose using a measuring cup. Do not use a household spoon because you may not get the correct dose. If your liquid form is a suspension, shake the bottle well before each dose.
Mode of Action
Pseudoephedrine is a sympathomimetic drug belonging to the phenethylamine and amphetamine chemical classes. Its principal mechanism of action depends on its effects on the adrenergic receptor system, causing vasoconstriction.
Chlorpheniramine binds to the histamine H1 receptor. This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms brought on by histamine. Well absorbed in the gastrointestinal tract.
Paracetamol has a central analgesic effect that is mediated through activation of descending serotonergic pathways. Debate exists about its primary site of action, which may be inhibition of prostaglandin (PG) synthesis or through an active metabolite influencing cannabinoid receptors.
Uses
This combination medication is used to temporarily treat symptoms caused by the common cold, flu, allergies, or other breathing illnesses (such as sinusitis, bronchitis).
Contraindications
Don't use this medicine if you have:
- Hypersensitivity to this medicine
Precautions and Warning
- Consult with your doctor if you are pregnant or breast feeding woman before taking this medicine to understand the risk and benefit ratio.
- Talk to your doctor about past medical history like kidney problem, heart problem or liver problem before taking this medicine
- Don't double the dose for the missed one.
- Complete the prescribed dose and duration of medicine. Do not stop taking the medication suddenly without talking to your doctor.
- Don't take for longer than 7 days in a row.
